VGLUT1 Recombinant Alpaca VHH (SdAb2412.VGLUT1) – MiniMab™

Recombinant Alpaca VHH targeting vesicular glutamate transporter 1 (VGLUT1), part of Biotium’s MiniMab™ SdAb series that have been engineered for optimal conjugate performance.

Name SKU Size Availability Vendor Price Order

CF®488A

 N003-488A-200UL 200uL Generally 1-2 weeks from receipt of order Biotium Log in for pricing

CF®498

 N003-498-200UL 200uL Generally 1-2 weeks from receipt of order Biotium Log in for pricing

CF®568

 N003-568-200UL 200uL Generally 1-2 weeks from receipt of order Biotium Log in for pricing

CF®583R

 N003-583R-200UL 200uL Generally 1-2 weeks from receipt of order Biotium Log in for pricing

CF®647

 N003-647-200UL 200uL Generally 1-2 weeks from receipt of order Biotium Log in for pricing

CF®660C

 N003-660C-200UL 200uL Generally 1-2 weeks from receipt of order Biotium Log in for pricing

CF®680

 N003-680-200UL 200uL Generally 1-2 weeks from receipt of order Biotium Log in for pricing

CF®740

 N003-740-200UL 200uL Generally 1-2 weeks from receipt of order Biotium Log in for pricing

Photos

Features

VGLUT1 Recombinant Alpaca VHH (SdAb2412.VGLUT1) recognizes the vesicular glutamate transporter 1 (VGLUT1) expressed during neurotransmission. This high-affinity single-domain antibody (SdAb), also known as camelid VHH or Nanobody®, is part of our MiniMab™ series of highly optimized conjugated probes. The SdAb has been validated for immunofluorescence microscopy and is available conjugated to CF® Dyes.

Features of MiniMab™ single-domain antibodies

  • Superior to conventional antibodies: deeper tissue penetration, higher solubility and stability, and faster staining
  • Minimal epitope-dye displacement—perfect for super-resolution imaging
  • Specifically developed and optimized for immunofluorescence
  • Labelled with bright, photostable CF® Dyes, including near-infrared CF®740 option
  • Available as conjugates with Biotium’s best-in-class dyes for STORM

VGLUT1 is mainly found on synaptic vesicles at glutamatergic synapses, where it uses the proton gradient generated by vesicular ATPase to load glutamate into vesicles before their fusion with the plasma membrane and neurotransmitter release into the synaptic cleft.

This recombinant alpaca VHH binds strongly and specifically to the cytoplasmic region of rat and mouse VGLUT1 and is expected to also recognize human VGLUT1 due to high sequence similarity.

Learn more about CF® Dyes for super-resolution as well as our innovative reagents for immunofluorescence microscopy; this includes our NucSpot® Nuclear Stains for bright and nuclear-specific staining in a wide colour selection, and CytoLiner™ Fixed Cell Membrane Stains for robust membrane staining in formaldehyde-fixed cells.

View Biotium’s full selection of primary and secondary antibodies available with bright CF® Dyes and other labels.

Resources

Protocols for Antibody Based Detection:

SDS:

Datasheet:

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